Doxefazepam

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Doxefazepam
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Systematic (IUPAC) name
9-chloro-6-(2-fluorophenyl)-4-hydroxy
-2-(2-hydroxyethyl)-2,5-diazabicyclo
[5.4.0]undeca-5,8,10,12-tetraen-3-one
Clinical data
Pregnancy
category
  •  ?
Routes of
administration
Oral
Legal status
Legal status
Pharmacokinetic data
Bioavailability ?
Metabolism Hepatic
Biological half-life 3-4 hours[1]
Excretion Renal
Identifiers
CAS Number 40762-15-0
ATC code N05CD12 (WHO)
PubChem CID 38668
DrugBank ?
Chemical data
Formula C17H14ClFN2O3
Molar mass 348.8[[Script error: No such module "String".]]
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Doxefazepam (marketed under brand name Doxans) is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is used therapeutically as a hypnotic.[2] According to Babbini and colleagues in 1975, this derivative of flurazepam was between 2 and 4 times more potent than the latter while at the same time being half as toxic in laboratory animals.[3]

See also

References

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External links


  1. http://www.intox.org/databank/documents/pharm/doxefzpm/iarc796.htm
  2. Rodriguez, G; Rosadini, G; Sannita, WG; Strumia, E (1984). "Effects of doxefazepam on normal sleep. An EEG and neuropsychological study". Neuropsychobiology. 11 (2): 133–9. PMID 6483162. 
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