Isopropamide
From Self-sufficiency
File:Isopropamide.png | |
Systematic (IUPAC) name | |
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4-amino-N,N-diisopropyl-N-methyl-4-oxo-3,3-diphenylbutan-1-aminium | |
Clinical data | |
Routes of administration | Oral |
Legal status | |
Legal status |
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Identifiers | |
CAS Number | 71-81-8 |
ATC code | A03AB09 (WHO) |
PubChem | CID 3775 |
Chemical data | |
Formula | C23H33N2O1 + |
Molar mass | 353.52092 g/mol |
Isopropamide is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders involving hyperacidity (gastrointestinal acidosis) and hypermotility. Chemically, it contains a quaternary ammonium group. It is most often provided as an iodide salt, but is also available as a bromide or chloride salt. It was discovered at Janssen Pharmaceutica in 1954.
References
- Seeherman R, Isopropamide iodide: a long-acting anticholinergic, Del Med J. 1957 Oct;29(10):265-9.
- Boss EG Jr, Buchanan GC, Effect of isopropamide iodide on basal gastric secretion in the human, Gastroenterology. 1957 Nov;33(5):730-6.
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