Mosapride

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Mosapride
180px
Systematic (IUPAC) name
(RS)-4-amino-5-chloro-2-ethoxy-N-{[4-(4-fluorobenzyl)morpholin-2-yl]methyl}benzamide
Identifiers
CAS Number 112885-41-3
ATC code none
PubChem CID 119584
IUPHAR/BPS 242
Chemical data
Formula C21H25ClFN3O3
Molar mass 421.893 g/mol[[Script error: No such module "String".]]
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Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist[1] which accelerates gastric emptying and is used for the treatment of acid reflux[2], irritable bowel syndrome and functional dyspepsia.[3]


References

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Drugs for
functional bowel disorders
Tertiary
amino group
Other
Belladonna and derivatives
(antimuscarinics)
tertiary amines: Atropine · Hyoscyamine
quaternary ammonium compounds: Scopolamine (Butylscopolamine, Methylscopolamine) · Methylatropine · Fentonium · Cimetropium bromide
Propulsives


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es:Mosapride ja:モサプリド
  1. ↑ Kato S, Morie T, Yoshida N. Synthesis and biological activities of metabolites of mosapride, a new gastroprokinetic agent. Chemical and Pharmaceutical Bulletin (Tokyo). 1995 Apr;43(4):699-702.
  2. ↑ Ruth M, Hamelin B, Rohss K, Lundell L. The effect of mosapride, a novel prokinetic, on acid reflux variables in patients with gastro-oesophageal reflux disease. Alimentary Pharmacology and Therapeutics. 1998 Jan;12(1):35-40.
  3. ↑ Mizuta Y, Shikuwa S, Isomoto H, Mishima R, Akazawa Y, Masuda J, Omagari K, Takeshima F, Kohno S. Recent insights into digestive motility in functional dyspepsia. Journal of Gastroenterology. 2006 Nov;41(11):1025-40.
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