Caroverine

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Caroverine
File:Caroverine.png
Systematic (IUPAC) name
1-[2-(diethylamino)ethyl]- 3-(4-methoxybenzyl)quinoxalin- 2(1H)-one
Clinical data
Routes of
administration		 Oral
Legal status
Legal status
  • ℞ (Prescription only)
Identifiers
CAS Number 23465-76-1
ATC code A03AX11 (WHO)
PubChem CID 65709
ChemSpider 59135
Chemical data
Formula C22H27N3O2
Molar mass 365.47 g/mol[[Script error: No such module "String".]]
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Caroverine (Spasmium, Spadon) is a drug used as a spasmolytic and otoneuroprotective (inner ear protective) agent in some countries.[1] It acts as an N-type calcium channel blocker, competitive AMPA receptor antagonist, and non-competitive NMDA receptor antagonist.[1] It also has potent antioxidant effects.[1][2]

References

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Peripherally acting
(primarily antinicotinic,
Neuromuscular junction block)
Tertiary amines / Non-curare alkaloids
ultra-short duration: Gantacurium

short duration: Mivacurium  · Chandonium

intermediate duration: Atracurium  · Cisatracurium  · Fazadinium  · Rocuronium  · Vecuronium  · Dipyrandium  · N,N'-Dimethylconessine  · Stercuronium  · Dacuronium  · Mytolon

long duration: Doxacurium · Dimethyltubocurarine · Pancuronium · Pipecuronium  · Laudexium  · Gallamine  · Benzoquinonium  · Decaethonium  · Succinyl-bis-β-phenylcholine  · Anatruxonium  · Truxilonium  · Cyclobutonium  · Dipyronium · Pyrocurinum  · Tercuronium  · Diadonium

unsorted: Hexafluronium (Hexafluorenium)  · Myanesin  · Cyclobutonium  · Mebutanium  · Amidonium  · Nubitanium  · Quilidium  · Decadonium
Clostridium botulinum toxin  · Atraxotoxin  · β-Bungarotoxin  · Black widow spider venom
Centrally acting
Other
Directly acting

M: MUS, DF+DRCT

anat (h/n, u, t/d, a/p, l)/phys/hist

noco(m, s, c)/cong(d)/tumr, sysi/epon, injr

proc, drug (M1A/3)

Selective
Dihydropyridines ("-dipine")
1-4 Benzothiazepines ("-tiazem")
Non-selective
Other/ungrouped
Amrinone  • Anandamide  • Anipamil  • Azimilide  • Bencyclane  • Bepridil  • Berbamine  • Bevantolol  • Canadine  • Carboxyamidotriazole  • Caroverine  • Cinnarizine  • Conotoxins  • Darodipine  • Dauricine  • Devapamil  • Dimeditiapramine  • Dotarizine  • Emopamil  • Enpiperate  • Eperisone  • Falipamil  • Fantofarone  • Fasudil  • Fenamic acid  • Fendiline  • Flunarizine  • Fostedil  • Gabapentin  • Lamotrigine  • Lidoflazine  • Magnesium sulfate  • Manoalide  • Mepirodipine  • Mibefradil‡  • Monatepil  • Naftopidil  • Niguldipine  • Niludipin  • Norverapamil  • Ochratoxin A  • Octylonium  • Osthol  • Oxodipine  • Perhexiline  • Pinaverium  • Piperidine  • Pregabalin  • Prenylamine  • Risedronic acid  • Ryodipine  • Sesamodil  • Stepholidine  • Terodiline  • Tetrahydropalmatine  • Tetrandrine  • Tolfenamic acid  • Tranilast


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  1. ↑ 1.0 1.1 1.2 Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
  2. ↑ Nohl H, Bieberschulte W, Dietrich B, Udilova N, Kozlov AV (2003). "Caroverine, a multifunctional drug with antioxidant functions". BioFactors. 19 (1-2): 79–85. doi:10.1002/biof.5520190110. PMID 14757980. 
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