Thiazide-like diuretic

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A thiazide-like diuretic is a sulfonamide diuretic that has similar physiological properties to a thiazide diuretic, but doesn't have the chemical properties of a thiazide, lacking the benzothiadiazine molecular structure.

Examples include chlorthalidone and metolazone.

Some, such as indapamide are considered thiazide-like diuretics, but don't necessarily have the same mechanism.[1]


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  1. MeSH Indapamide