Chlortetracycline
From Self-sufficiency
File:Chlortetracycline.svg | |
Systematic (IUPAC) name | |
---|---|
(4S,4aS,5aS,6S,12aS,Z)-2-[amino(hydroxy)methylene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydrotetracene-1,3,12(2H,4H,12aH)-trione | |
Clinical data | |
Routes of administration | Oral, IV, topical |
Pharmacokinetic data | |
Bioavailability | 30% |
Protein binding | 50 to 55% |
Metabolism | Hepatic (75%) |
Biological half-life | 5.6 to 9 hours |
Excretion | Renal and biliary |
Identifiers | |
CAS Number | 57-62-5 |
ATC code | A01AB21 (WHO) D06AA02 J01AA03 S01AA02 QJ51AA03 |
Chemical data | |
Formula | C22H23ClN2O8 |
Molar mass | 478.88 g/mol[[Script error: No such module "String".]] |
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Chlortetracycline (trade name Aureomycin, Lederle) is a tetracycline antibiotic, and was the first tetracycline to be discovered. It was discovered in 1945 by Dr Benjamin Duggar in a soil sample from Sanborn Field at the University of Missouri, yielding an actinomycete, Streptomyces aureofaciens (hence the name Aureomycin). In veterinary medicine, it is commonly used to treat conjunctivitis in cats.[1]
References
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