Chlortetracycline

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Chlortetracycline
File:Chlortetracycline.svg
Systematic (IUPAC) name
(4S,4aS,5aS,6S,12aS,Z)-2-[amino(hydroxy)methylene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydrotetracene-1,3,12(2H,4H,12aH)-trione
Clinical data
Routes of
administration
Oral, IV, topical
Pharmacokinetic data
Bioavailability 30%
Protein binding 50 to 55%
Metabolism Hepatic (75%)
Biological half-life 5.6 to 9 hours
Excretion Renal and biliary
Identifiers
CAS Number 57-62-5
ATC code A01AB21 (WHO) D06AA02 J01AA03 S01AA02 QJ51AA03
Chemical data
Formula C22H23ClN2O8
Molar mass 478.88 g/mol[[Script error: No such module "String".]]
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Chlortetracycline (trade name Aureomycin, Lederle) is a tetracycline antibiotic, and was the first tetracycline to be discovered. It was discovered in 1945 by Dr Benjamin Duggar in a soil sample from Sanborn Field at the University of Missouri, yielding an actinomycete, Streptomyces aureofaciens (hence the name Aureomycin). In veterinary medicine, it is commonly used to treat conjunctivitis in cats.[1]

References

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cs:Chlortetracyklin

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zh:金霉素
  1. Merck Veterinary Manual.