NNC 38-1049
From Self-sufficiency
NNC 38-1049 | |
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File:NNC38-1049 structure.png | |
1-(4-chlorophenyl)-4-(4-cyclopentylpiperazine-1-yl)-4-oxobutan-1-one | |
style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers | |
CAS number | 757183-18-9 |
SMILES | Script error: No such module "collapsible list". |
style="background: #F8EABA; text-align: center;" colspan="2" | Properties | |
Molecular formula | C19H25ClN2O2 |
Molar mass | 348.866 g/mol |
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
Infobox references |
NNC 38-1049 is a histamine antagonist selective for the H3 subtype. It has anorectic effects in animal studies and is being researched as a potential treatment for obesity.[1][2]
References
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- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
- ↑ Malmlöf K, Golozoubova V, Peschke B, Wulff BS, Refsgaard HH, Johansen PB, Cremers T, Rimvall K. Increase of neuronal histamine in obese rats is associated with decreases in body weight and plasma triglycerides. Obesity (Silver Spring). 2006 Dec;14(12):2154-62. PMID 17189541