Mepyramine

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Mepyramine
File:Mepyramine.svg
Systematic (IUPAC) name
N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine
Identifiers
CAS Number 91-84-9
59-33-6 (maleate)
ATC code R06AC01 (WHO) D04AA02
PubChem CID 4992
IUPHAR/BPS 1220
Synonyms N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine
Chemical data
Formula C17H23N3O
Molar mass 285.38 g/mol[[Script error: No such module "String".]]
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Mepyramine, also known as pyrilamine, is a first generation antihistamine, targeting the H1 receptor.[1] However, it rapidly permeates the brain often causing drowsiness. It also has anticholinergic properties. It is used in over-the-counter combination products to treat the common cold and menstrual symptoms.[2] It is also the active ingredient of the topical antihistamine cream Anthisan, sold for the treatment of insect bites, stings and nettle rash.

References

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  1. Parsons, M. E. and Ganellin, C. R. (2006). "Histamine and its receptors". British Journal of Pharmacology. 147: S127–S135. doi:10.1038/sj.bjp.0706440. PMC 1760721Freely accessible. PMID 16402096. 
  2. Active Ingredients for Midol Complete