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Systematic (IUPAC) name
2,2'-(2-hydroxyethylimino)bis [N-(1,1-dimethyl-2- phenylethyl)-N-methylacetamide]
Clinical data
Routes of
Oral, topical
Pharmacokinetic data
Biological half-life 1 hour
CAS Number 126-27-2
ATC code C05AD06 (WHO)
PubChem CID 4621
Chemical data
Formula C28H41N3O3
Molar mass 467.643 g/mol[[Script error: No such module "String".]]
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Oxetacaine (INN, also known as oxethazaine) is a potent local anesthetic. It is administered orally (usually in combination with an antacid) for the relief of pain associated with peptic ulcer disease or esophagitis. It is also used topically in the management of hemorrhoid pain. Oral oxetacaine preparations are available in several countries, including India, South Africa, Japan and Brazil, but not the United States; oxetacaine was withdrawn from the UK market in 2002.

Unlike most local anesthetics, oxetacaine is active even in strongly acidic conditions.[1]


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External links

  1. Seifter J, Glassman JM, Hudyma GM (1962). "Oxethazaine and related congeners: a series of highly potent local anesthetics". Proc Soc Exp Biol Med. 109: 664–8. PMID 13910333.