Cinchocaine

Cinchocaine

File:Cinchocaine.svg
Systematic (IUPAC) name
2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide
Clinical data
Routes of administration	topical, intravenous (equine euthanasia)
Identifiers
CAS Number	85-79-0
ATC code	C05AD04 (WHO) D04AB02 N01BB06 S01HA06
PubChem	CID 3025
DrugBank	APRD00915
ChemSpider	2917
Chemical data
Formula	C20H29N3O2
Molar mass	343.463 g/mol[[]]
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Cinchocaine (or Dibucaine) is an amide local anesthetic. It is the active ingredient in some topical hemorrhoid creams such as Proctosedyl. It is sold under the brand names Cincain, Nupercainal, Nupercaine and Sovcaine [1].

Dibucaine is insoluble in alkaline aquatic environments.

It is also a component of the veterinary drug Somulose, used for euthanasia of horses and cattle.

External links

• Abdel-Ghani N, Youssef A, Awady M (2005). "Cinchocaine hydrochloride determination by atomic absorption spectrometry and spectrophotometry". Farmaco. 60 (5): 419–24. doi:10.1016/j.farmac.2005.03.001. PMID 15910814. CS1 maint: Multiple names: authors list (link)
• Souto-Padron T, Lima AP, de Oliveira Ribeiro R. (2006). "Effects of dibucaine on the endocytic/exocytic pathways in Trypanosoma cruzi". Parasitol Res. 99 (4): 317. doi:10.1007/s00436-006-0192-1. PMID 16612626. CS1 maint: Multiple names: authors list (link)
• Nounou M, El-Khordagui L, Khalafallah N (2005). "Effect of various formulation variables on the encapsulation and stability of dibucaine base in multilamellar vesicles". Acta Pol Pharm. 62 (5): 369–79. PMID 16459486. CS1 maint: Multiple names: authors list (link)

de:Dibucain