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Systematic (IUPAC) name
2-(dimethylamino)ethyl 4-(butylamino)benzoate
Clinical data
Routes of
Topical, Epidural, Spinal
Legal status
Legal status
  • ℞ (Prescription only)
Pharmacokinetic data
Protein binding 75.6
CAS Number 94-24-6
136-47-0 (hydrochloride)
ATC code C05AD02 (WHO) D04AB06 N01BA03 S01HA03
PubChem CID 5411
Chemical data
Formula C15H24N2O2
Molar mass 264.363 g/mol[[Script error: No such module "String".]]
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Tetracaine (INN, also known as amethocaine; trade name Pontocaine and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely[1].


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fr:Tétracaïne hu:Tetrakain ja:テトラカイン

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