Phenazone

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Phenazone
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Systematic (IUPAC) name
1,2-dihydro- 1,5-dimethyl- 2-phenyl- 3H-pyrazol- 3-one
Identifiers
CAS Number 60-80-0
ATC code N02BB01 (WHO) S02DA03
PubChem CID 2206
DrugBank DB01435
ChemSpider 2121
Synonyms analgesine, antipyrine
Chemical data
Formula C11H12N2O
Molar mass 188.226 g/mol[[Script error: No such module "String".]]
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Phenazone (INN), phenazon, antipyrine (USAN), or analgesine is an analgesic and antipyretic. It was first synthesized by Ludwig Knorr in 1883.[1] It is formed by reducing diortho- dinitrodiphenyl with sodium amalgam and methyl alcohol, or by heating diphenylene-ortho-dihydrazine with hydrochloric acid to 150 °C. It crystallizes in needles which melt at 156 °C. Potassium permanganate oxidizes it to pyridazine tetracarboxylic acid.

Adverse effects

Possible adverse effects include:[citation needed]

See also

References

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es:Fenazona fr:Phénazone it:Fenazone nl:Antipyrine ja:アンチピリン pl:Fenazon ru:Феназон fi:Antipyriini

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  1. Brune, K (1997). "The early history of non-opioid analgesics". Acute Pain. 1: 33. doi:10.1016/S1366-0071(97)80033-2.