Difference between revisions of "Phenazone"

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Latest revision as of 21:04, 21 September 2010

Phenazone
Systematic (IUPAC) name
200px
1,2-dihydro- 1,5-dimethyl- 2-phenyl- 3H-pyrazol- 3-one
Identifiers
CAS Number	60-80-0
ATC code	N02BB01 (WHO) S02DA03
PubChem	CID 2206
DrugBank	DB01435
ChemSpider	2121
Synonyms	analgesine, antipyrine
Chemical data
Formula	C₁₁H₁₂N₂O
Molar mass	188.226 g/mol[[Script error: No such module "String".]]
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Phenazone (INN), phenazon, antipyrine (USAN), or analgesine is an analgesic and antipyretic. It was first synthesized by Ludwig Knorr in 1883.^[1] It is formed by reducing diortho- dinitrodiphenyl with sodium amalgam and methyl alcohol, or by heating diphenylene-ortho-dihydrazine with hydrochloric acid to 150 °C. It crystallizes in needles which melt at 156 °C. Potassium permanganate oxidizes it to pyridazine tetracarboxylic acid.

Adverse effects

Possible adverse effects include:^{[citation needed]}

References

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Analgesics (N02A, N02B)

Opioids
See also: Opioids template

Opium & alkaloids thereof	Codeine · Morphine · Opium · Laudanum · Paregoric
Semi-synthetic opium derivatives	Acetyldihydrocodeine · Benzylmorphine · Buprenorphine · Desomorphine · Dihydrocodeine · Dihydromorphine · Ethylmorphine · Diamorphine · Hydrocodone · Hydromorphinol · Hydromorphone · Nicocodeine · Nicodicodeine · Nicomorphine · Oxycodone · Oxymorphone
Synthetic opioids	Alphaprodine · Anileridine · Butorphanol · Dextromoramide · Dextropropoxyphene · Dezocine · Fentanyl · Ketobemidone · Levorphanol · Methadone · Meptazinol · Nalbuphine · Pentazocine · Propoxyphene · Propiram · Pethidine · Phenazocine · Piminodine · Piritramide · Tapentadol · Tilidine · Tramadol

Pyrazolones

Ampyrone/Aminophenazone · Metamizole · Phenazone · Propyphenazone

Cannabinoids

Ajulemic acid · AM404 · Cannabidiol · Cannabis · Nabilone · Nabiximols · Tetrahydrocannabinol

Anilides

Paracetamol (acetaminophen) · Phenacetin · Propacetamol

Non-steroidal
anti-inflammatories
See also: NSAIDs template

Propionic acid class	Fenoprofen · Flurbiprofen · Ibuprofen · Ketoprofen · Naproxen · Oxaprozin
Oxicam class	Meloxicam · Piroxicam
Acetic acid class	Diclofenac · Indometacin · Ketorolac · Nabumetone · Sulindac · Tolmetin
COX-2 inhibitors	Celecoxib · Rofecoxib · Valdecoxib · Parecoxib · Lumiracoxib
Anthranilic acid (fenamate) class	Meclofenamate · Mefenamic acid
Salicylates	Aspirin (Acetylsalicylic acid) · Benorylate · Diflunisal · Ethenzamide · Magnesium salicylate · Salicin · Salicylamide · Salsalate · Trisalate · Wintergreen (Methyl salicylate)

Atypical, Adjuvant & Potentiators,
Metabolic agents and miscellaneous

Amitryptiline · Befiradol · Bicifadine · Carisoprodol · Camphor · Cimetidine · Clonidine · Chlorzoxazone · Cyclobenzaprine · Duloxetine · Esreboxetine · Flupirtine · Gabapentin · Glafenine · Hydroxyzine · Ketamine · Menthol · Mephenoxalone · Methocarbamol · Nefopam · Orphenadrine · Pregabalin · Proglumide · Scopolamine · Tebanicline · Trazodone · XP-13512 (Gabapentin enacarbil) · Ziconotide

M: CNS

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Otologicals (S02)

Anti-infectives

Acetic acid • Aluminium acetotartrate • Boric acid • Chloramphenicol • Chlorhexidine • Ciprofloxacin • Clioquinol • Gentamicin • Hydrogen peroxide • Miconazole • Neomycin • Nitrofurazone • Ofloxacin • Polymyxin B • Rifamycin • Tetracycline

Corticosteroids

Betamethasone • Dexamethasone • Fluocinolone acetonide • Hydrocortisone • Prednisolone

Analgesics and anesthetics

Lidocaine • Cocaine • Phenazone

M: EAR

anat(e, p)/phys/devp

noco/cong, epon

proc, drug(S2)

40px	This analgesic-related article is a stub. You can help ssf by expanding it. v d e

de:Phenazon

es:Fenazona fr:Phénazone it:Fenazone nl:Antipyrine ja:アンチピリン pl:Fenazon ru:Феназон fi:Antipyriini

tr:Antipirin

↑ Brune, K (1997). "The early history of non-opioid analgesics". Acute Pain. 1: 33. doi:10.1016/S1366-0071(97)80033-2.

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Difference between revisions of "Phenazone"

Latest revision as of 21:04, 21 September 2010

Adverse effects

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References

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