Loxtidine

From Self-sufficiency
Revision as of 06:29, 14 April 2010 by حسن علي البط (Talk) (Adding category Category:Phenol ethers (using HotCat))

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Loxtidine
File:Loxtidine structure.png
Systematic (IUPAC) name
[1-methyl-5-({3-[3-(piperidin-1-ylmethyl)phenoxy]propyl}amino)-1H-1,2,4-triazol-3-yl]methanol
Clinical data
Routes of
administration		 Oral
Legal status
Legal status
  • Uncontrolled
Identifiers
CAS Number 76956-02-0
ATC code none
PubChem CID 55473
ChemSpider 50093
Chemical data
Formula C19H29N5O2
Molar mass 359.47 g/mol[[Script error: No such module "String".]]
Script error: No such module "collapsible list".
Script error: No such module "TemplatePar".Expression error: Unexpected < operator.

Loxtidine (INN), also known as lavoltidine (USAN, BAN) or AH-23,844, is a highly potent and selective H2 receptor antagonist which was under development as a treatment for gastroesophageal reflux disease but was discontinued due to the discovery that it produced gastric carcinoid tumors in rodents.[1][2]

Synthesis

450px[3]

See also

References

Cite error: Invalid <references> tag; parameter "group" is allowed only.

Use <references />, or <references group="..." />


H2 antagonists ("-tidine")
Prostaglandins (E)/analogues ("-prost-")
Proton-pump inhibitors ("-prazole")
Other
  1. ↑ Washington, Neena (1991). Antacids and anti-reflux agents. Boca Raton: CRC Press. ISBN 0-8493-5444-7. 
  2. ↑ Dictionary of organic compounds. London: Chapman & Hall. 1996. ISBN 0-412-54090-8. 
  3. ↑ Cliterow, J. W.; Bradshaw, J.; Price, B. J.; Martin-Smith, M.; Mackinon, J. W. M.; Judd, D. B.; Hayes, R.; Carey, L.; 1983, EP 0016565 .
Retrieved from "http://ssf.f15ijp.com/wiki/index.php?title=Loxtidine&oldid=23950"