Sulfadiazine

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Sulfadiazine
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Systematic (IUPAC) name
4-amino-N-pyrimidin- 2-yl-benzenesulfonamide
Clinical data
Pregnancy
category
  •  ?
Routes of
administration		 Cream
Legal status
Legal status
  • Approved Drug
Pharmacokinetic data
Bioavailability ?
Metabolism ?
Biological half-life ?
Excretion ?
Identifiers
CAS Number 68-35-9
ATC code J01EC02 (WHO) QJ01EQ10
PubChem CID 5215
DrugBank APRD00190
Chemical data
Formula C10H10N4O2S
Molar mass 250.278 g/mol[[Script error: No such module "String".]]
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Sulfadiazine is a sulfonamide antibiotic.

Uses

It eliminates bacteria that cause infections by stopping the production of folic acid inside the bacterial cell, and is commonly used to treat urinary tract infections (UTIs).

In combination, sulfadiazine and pyrimethamine, can be used to treat toxoplasmosis, a disease caused by Toxoplasma gondii.

Side effects

Side effects reported for sulfadiazine include: nausea, upset stomach, loss of appetite, and dizziness.

Brand names

Lantrisul; Neotrizine; Sulfa-Triple #2; Sulfadiazine; Sulfaloid; Sulfonamides Duplex; Sulfose; Terfonyl; Triple Sulfa; Triple Sulfas; Triple Sulfoid

See also

External links


Antifolates
(inhibits
purine metabolism,
thereby inhibiting
DNA and RNA synthesis)
Sulfamethoxazole · Sulfadiazine# · Sulfamoxole
Other/ungrouped
Combinations
Topoisomerase
inhibitors/
quinolones/
(inhibits
DNA replication)
Related agents (DG)
Anaerobic DNA
inhibitors
Nitro- imidazole derivatives
Nitrofuran derivatives
RNA synthesis

M: BAC

drug(J1p, w, n, m, vacc)

Alveo-
late
Pyrimethamine • Sulfadiazine
Individual
agents
Other
Lumefantrine (combined with artemether as Coartem)
Halofantrine
DHFR inhibitors
(antifols)
Combination
Fansidar# (pyrimethamine-sulfadoxine)
Other
Atovaquone (always combined with proguanil as Malarone)
Tetracycline • Doxycycline#
Clindamycin
Combi-
nations
Fixed-dose (coformulated) ACTs
Coartem# • ASAQ (Coarsucam) • ASMQ •
Duo-Cotecxin (Artekin) • Pyramax
Combination therapies
(not co-formulated)
Quinine/tetracycline • Quinine/clindamycin •
Artequin • Ariplus • Co-Arinate • CDA
Hetero-
kont


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