Sabeluzole

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Sabeluzole
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Systematic (IUPAC) name
1-[4-[1,3-benzothiazol-2-yl(methyl)amino]piperidin-1-yl]-3-(4-fluorophenoxy)propan-2-ol
Legal status
Legal status
  • Unscheduled
Identifiers
CAS Number 104383-17-7
ATC code none
PubChem CID 59823
Chemical data
Formula C22H26FN3O2S
Molar mass 415.524 g/mol[[Script error: No such module "String".]]
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Sabeluzole (R-58,735) is a nootropic and neuroprotective drug which was originally developed for the treatment of Alzheimer's disease,[1][2] and has subsequently been researched for other applications such as sleep apnoea.[3] It acts primarily as an NMDA antagonist,[4] but other mechanisms of action may also be important.[5][6]


See also

References

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  1. Clincke GH, Tritsmans L, Idzikowski C, Amery WK, Janssen PA (1988). "The effect of R 58 735 (Sabeluzole) on memory functions in healthy elderly volunteers". Psychopharmacology. 94 (1): 52–7. PMID 3126527. 
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  5. Geerts H, Nuydens R, De Jong M, Cornelissen F, Nuyens R, Wouters L (1996). "Sabeluzole stabilizes the neuronal cytoskeleton". Neurobiology of Aging. 17 (4): 573–81. PMID 8832632. 
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