Sabeluzole
From Self-sufficiency
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Systematic (IUPAC) name | |
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1-[4-[1,3-benzothiazol-2-yl(methyl)amino]piperidin-1-yl]-3-(4-fluorophenoxy)propan-2-ol | |
Legal status | |
Legal status |
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Identifiers | |
CAS Number | 104383-17-7 |
ATC code | none |
PubChem | CID 59823 |
Chemical data | |
Formula | C22H26FN3O2S |
Molar mass | 415.524 g/mol[[Script error: No such module "String".]] |
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Sabeluzole (R-58,735) is a nootropic and neuroprotective drug which was originally developed for the treatment of Alzheimer's disease,[1][2] and has subsequently been researched for other applications such as sleep apnoea.[3] It acts primarily as an NMDA antagonist,[4] but other mechanisms of action may also be important.[5][6]
See also
References
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This pharmacology-related article is a stub. You can help ssf by expanding it. |
- ↑ Clincke GH, Tritsmans L, Idzikowski C, Amery WK, Janssen PA (1988). "The effect of R 58 735 (Sabeluzole) on memory functions in healthy elderly volunteers". Psychopharmacology. 94 (1): 52–7. PMID 3126527.
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- ↑ Geerts H, Nuydens R, De Jong M, Cornelissen F, Nuyens R, Wouters L (1996). "Sabeluzole stabilizes the neuronal cytoskeleton". Neurobiology of Aging. 17 (4): 573–81. PMID 8832632.
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