Quazinone
From Self-sufficiency
Revision as of 21:07, 21 June 2010 by Anypodetos (Talk) (Adding category Category:PDE3 inhibitors (using HotCat))
| File:Quazinone structure.png | |
| Systematic (IUPAC) name | |
|---|---|
|
(3R)-6-chloro-3-methyl-5,10-dihydroimidazo[2,1-b]quinazolin-2(3H)-one | |
| Clinical data | |
| Routes of administration | Oral |
| Legal status | |
| Legal status |
|
| Identifiers | |
| CAS Number | 70018-51-8 |
| ATC code | none |
| PubChem | CID 6603980 |
| ChemSpider | 5036286 |
| Synonyms | Ro 13-6438 |
| Chemical data | |
| Formula | C11H10ClN3O |
| Molar mass | 235.67 g/mol[[Script error: No such module "String".]] |
| Script error: No such module "collapsible list". | |
Quazinone (Dozonone, Posicor) is a cardiotonic and vasodilator drug which was developed and marketed in the 1980s for the treatment of heart disease.[1][2][3][4][5] It acts as a selective PDE3 inhibitor.[6][7] It is no longer available.[1]
Synthesis
See also
References
Cite error: Invalid <references> tag;
parameter "group" is allowed only.
<references />, or <references group="..." />
- ↑ 1.0 1.1 David J. Triggle (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC. ISBN 0-412-46630-9.
- ↑ Eigenmann R, Gerold M, Holck M (1984). "Cardiovascular profile of Ro 13-6438, a novel positive inotropic agent with vasodilating properties". Journal of Cardiovascular Pharmacology. 6 (3): 511–9. PMID 6202980.
- ↑ Holck M, Thorens S, Muggli R, Eigenmann R (1984). "Studies on the mechanism of positive inotropic activity of Ro 13-6438, a structurally novel cardiotonic agent with vasodilating properties". Journal of Cardiovascular Pharmacology. 6 (3): 520–30. PMID 6202981.
- ↑ Belz GG, Stern HC, Butzer R (1985). "Dose-response following single administrations of a new cardiac performance enhancer RO 13-6438 in normal volunteers". Journal of Cardiovascular Pharmacology. 7 (1): 86–90. PMID 2580156.
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
- ↑ Chodnekar, M. S.; Kaiser, A.; 1981, U.S. Patent 4,256,748
Categories:
- Pages with script errors
- Pages with broken file links
- Drugs with non-standard legal status
- Infobox drug tracked parameters
- Articles without EBI source
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without InChI source
- Articles without UNII source
- Drugs not assigned an ATC code
- Articles containing unverified chemical infoboxes
- 2Fix
- Inotropic agents
- Vasodilators
- Lactams
- Imidazoquinazolines
- Organochlorides
- PDE3 inhibitors
- CS1 maint: Multiple names: authors list
