A-41988

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A-41988
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Systematic (IUPAC) name
8-[5-(4-fluorophenyl)pentan-2-yl]-5,5-dimethyl-2-prop-2-ynyl-3,4-dihydro-1H-chromeno[4,3-c]pyridin-10-ol
Identifiers
CAS Number 52763-30-1
PubChem CID 3085018
Chemical data
Formula C28H32FNO2
Molar mass 433.556 g/mol[[Script error: No such module "String".]]
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A-41988 (BW29Y) is an analgesic drug which acts as a cannabinoid agonist. It was developed by Abbott Laboratories in the 1970s,[1][2] and researched for potential use in the treatment of glaucoma,[3] but never commercialised.

References

  1. ↑ Winn, M; Arendsen, D; Dodge, P; Dren, A; Dunnigan, D; Hallas, R; Hwang, K; Kyncl, J; Lee, YH (1976). "Drugs derived from cannabinoids. 5. Delta6a,10a-Tetrahydrocannabinol and heterocyclic analogs containing aromatic side chains". Journal of Medicinal Chemistry. 19 (4): 461–71. doi:10.1021/jm00226a003. PMID 817021.  edit
  2. ↑ Guterman A, Somani P, Bachand RT. Clinical Pharmacology and Therapeutics 1979; 25:227.
  3. ↑ Tiedeman, JS; Shields, MB; Weber, PA; Crow, JW; Cocchetto, DM; Harris, WA; Howes, JF (1981). "Effect of synthetic cannabinoids on elevated intraocular pressure". Ophthalmology. 88 (3): 270–7. PMID 7015221.  edit
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