AM-906
From Self-sufficiency
| 240px | |
| Systematic (IUPAC) name | |
|---|---|
|
(6aR,9R,10aR)-3-[(Z)-hept-1-enyl]-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol | |
| Identifiers | |
| PubChem | CID 10089808 |
| Chemical data | |
| Formula | C23H34O3 |
| Molar mass | 358.513 g/mol[[Script error: No such module "String".]] |
| Script error: No such module "collapsible list". | |
AM-906 is an analgesic drug which is a cannabinoid agonist with a conformationally restricted side chain. It is a potent and selective agonist for the CB1 cannabinoid receptor, with a Ki of 0.8nM at CB1 vs 9.5nM at CB2, a selectivity of almost 12x.[1]
| 40px | This article about a cannabinoid is a stub. You can help ssf by expanding it. |
References
- ↑ Papahatjis DP, Kourouli T, Abadji V, Goutopoulos A, Makriyannis A. Pharmacophoric requirements for cannabinoid side chains: multiple bond and C1'-substituted delta 8-tetrahydrocannabinols. Journal of Medicinal Chemistry. 1998 Mar 26;41(7):1195-200. PMID 9544219
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