Bepridil

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Bepridil
File:Bepridil.svg
Systematic (IUPAC) name
N-benzyl-N-(3-isobutoxy-2-pyrrolidin-1-yl-propyl)aniline
Clinical data
Pregnancy
category
  • US: C (Risk not ruled out)
Routes of
administration
Oral
Pharmacokinetic data
Bioavailability Well absorbed
Protein binding 99%
Metabolism Hepatic, CYP3A4-mediated
Biological half-life 42 hours
Excretion Renal
Identifiers
CAS Number 64706-54-3
ATC code C08EA02 (WHO)
PubChem CID 2351
DrugBank APRD00727
ChemSpider 2261
Chemical data
Formula C24H34N2O
Molar mass 366.54 g/mol[[Script error: No such module "String".]]
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Bepridil (trade name Vascor) is a calcium channel blocker once used to treat angina. It is no longer sold in the United States.

It is nonselective.[1]

It has been discussed as a possible option in the treatment of atrial fibrillation.[2]

It has been implicated in causing the ventricular arrythmia [Torsade de Pointes] Torsade de pointes.

References

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External links


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