Tolfenamic acid

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Tolfenamic acid
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Systematic (IUPAC) name
2-[(3-chloro-2-methylphenyl)amino]benzoic acid)[1]
Clinical data
Routes of
administration
oral
Identifiers
CAS Number 13710-19-5
ATC code M01AG02 (WHO)
PubChem CID 610479
Chemical data
Formula C14H12ClNO2
Molar mass 261.707 g/mol[[Script error: No such module "String".]]
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Tolfenamic acid (TA) is one of the class of non-steroidal anti-inflammatory drugs (NSAIDs). It is used to treat the symptoms of migraine.

Other possible uses

A study concludes, "TA was found significantly better than placebo in the subjective evaluation of drug efficacy (p<0.001) and in reducing the reported hangover symptoms in general (p < 0.01). In the TA group, significantly lower symptom scores were obtained for headache (p<0.01), and for nausea, vomiting, irritation, tremor, thirst and dryness of mouth (all p < 0.05)."[1]

Commercial names

Commercial names for tolfenamic acid include Clotam Rapid and Tufnil. This drug should not be confused with Tolmetin.

References

  1. 1.0 1.1 Kim Vilbour Andersen, Sine Larsen, Børge Alhede, Niels Gelting and Ole Buchardt (1989). "Characterization of two polymorphic forms of tolfenamic acid, N-(2-methyl-3-chlorophenyl)anthranilic acid: their crystal structures and relative stabilities". J. Chem. Soc., Perkin Trans. 2: 1443–1447. doi:10.1039/P29890001443. 

External links


de:Tolfenaminsäure

fi:Tolfenaamihappo ru:Клотам