Mibefradil

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Mibefradil
File:Mibefradil.png
Systematic (IUPAC) name
(1S,2S)-2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl) (methyl)amino)ethyl)-6-fluoro-1-isopropyl- 1,2,3,4-tetrahydronaphthalen-2-yl 2-methoxyacetate
Clinical data
Routes of
administration
Oral
Legal status
Legal status
  • Withdrawn from market
Identifiers
CAS Number 116644-53-2
ATC code C08CX01 (WHO)
PubChem CID 60662
Chemical data
Formula C29H38FN3O3
Molar mass 495.63 g/mol[[Script error: No such module "String".]]
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Mibefradil (Posicor) is a drug for the treatment of hypertension and chronic angina pectoris. It belongs to a group known as calcium channel blockers.

It is nonselective.[1]

On June 8, 1998, Roche announced the voluntary withdrawal of the drug from the market,[2] due to the potential for drug interactions, some of them serious, which may occur when it is taken together with some other medications.

References

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  2. Letter from Roche Laboratories: http://www.fda.gov/medwatch/SAFETY/1998/poscor.htm