Nisoldipine

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Nisoldipine
File:Nisoldipine.svg
Systematic (IUPAC) name
isobutyl methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Clinical data
Pregnancy
category
  • US: C (Risk not ruled out)
Routes of
administration
Oral
Legal status
Legal status
Pharmacokinetic data
Protein binding 99%
Biological half-life 7-12 hours
Identifiers
CAS Number 63675-72-9
ATC code C08CA07 (WHO)
PubChem CID 4499
DrugBank APRD00635
Chemical data
Formula C20H24N2O6
Molar mass 388.414 g/mol[[Script error: No such module "String".]]
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Nisoldipine (INN) is a calcium channel blocker of the dihydropyridine class. It sold in the United States under the proprietary name Sular.

External links

  • DDB 30009
  • Mielcarek J, Grobelny P, Szamburska O (2005). "The effect of beta-carotene on the photostability of nisoldipine". Methods Find Exp Clin Pharmacol. 27 (3): 167–71. doi:10.1358/mf.2005.27.3.890873. PMID 15834448. 
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  • Hamilton S, Houle L, Thadani U (1999). "Rapid-release and coat-core formulations of nisoldipine in treatment of hypertension, angina, and heart failure". Heart Dis. 1 (5): 279–88. PMID 11720635. 


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