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Systematic (IUPAC) name
2-[4-(diphenylmethyl)piperazin-1-yl]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Legal status
Legal status
  • ℞ (Prescription only)
CAS Number 89226-50-6 120092-68-4
ATC code C08CA11 (WHO)
PubChem CID 4008
Chemical data
Formula C35H38N4O6
Molar mass 610.69 g/mol[[Script error: No such module "String".]]
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Manidipine (INN) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive[1][2][3][4][5]

Currently Manidipine is marketed by:

-Greek Pharmaceutical group Chiesi Hellas under the brands Manyper, Artedil, Manivasc and Iperten(formerly sold by Torrex Pharma GmbH, now owned by Chiesi Hellas), in Germany, Greece, France, Austria, Spain, Italy and Brazil.

-Takeda Chemical Industries, under the brands Vascoman, Calslot, and Madiplot, in Italy, Japan, Philippines and Thailand.


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  1. Cheer, S.M.; McClellan, K. (2001), "Manidipine: A Review of its Use in Hypertension", Drugs, 61 (12): 1777, PMID 11693466, retrieved 2009-06-20 
  2. McKeage, K.; Scott, L.J. (2004), "Manidipine: A Review of its Use in the Management of Hypertension", Drugs, 64 (17): 1923, PMID 15329044, retrieved 2009-06-20 
  3. Roca-cusachs, A.; Triposkiadis, F. (2005), "Antihypertensive Effect of Manidipine", Drugs, 65: 11, PMID 16398058, retrieved 2009-06-20 
  4. Otero, M.L. (2007), "Manidipine-delapril combination in the management of hypertension", Vascular Health and Risk Management, 3 (3): 255, PMC 2293964Freely accessible, PMID 17703633, retrieved 2009-06-20 
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