Difference between revisions of "Bepridil"

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Bepridil
File:Bepridil.svg
Systematic (IUPAC) name
N-benzyl-N-(3-isobutoxy-2-pyrrolidin-1-yl-propyl)aniline
Clinical data
Pregnancy
category
  • US: C (Risk not ruled out)
Routes of
administration		 Oral
Pharmacokinetic data
Bioavailability Well absorbed
Protein binding 99%
Metabolism Hepatic, CYP3A4-mediated
Biological half-life 42 hours
Excretion Renal
Identifiers
CAS Number 64706-54-3
ATC code C08EA02 (WHO)
PubChem CID 2351
DrugBank APRD00727
ChemSpider 2261
Chemical data
Formula C24H34N2O
Molar mass 366.54 g/mol[[Script error: No such module "String".]]
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Bepridil (trade name Vascor) is a calcium channel blocker once used to treat angina. It is no longer sold in the United States.

It is nonselective.[1]

It has been discussed as a possible option in the treatment of atrial fibrillation.[2]

It has been implicated in causing the ventricular arrythmia [Torsade de Pointes] Torsade de pointes.

References

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External links

Selective
Dihydropyridines ("-dipine")
1-4 Benzothiazepines ("-tiazem")
Non-selective
Fendiline • Bepridil • Lidoflazine • Perhexiline
Other/ungrouped
Amrinone  • Anandamide  • Anipamil  • Azimilide  • Bencyclane  • Bepridil  • Berbamine  • Bevantolol  • Canadine  • Carboxyamidotriazole  • Caroverine  • Cinnarizine  • Conotoxins  • Darodipine  • Dauricine  • Devapamil  • Dimeditiapramine  • Dotarizine  • Emopamil  • Enpiperate  • Eperisone  • Falipamil  • Fantofarone  • Fasudil  • Fenamic acid  • Fendiline  • Flunarizine  • Fostedil  • Gabapentin  • Lamotrigine  • Lidoflazine  • Magnesium sulfate  • Manoalide  • Mepirodipine  • Mibefradil‡  • Monatepil  • Naftopidil  • Niguldipine  • Niludipin  • Norverapamil  • Ochratoxin A  • Octylonium  • Osthol  • Oxodipine  • Perhexiline  • Pinaverium  • Piperidine  • Pregabalin  • Prenylamine  • Risedronic acid  • Ryodipine  • Sesamodil  • Stepholidine  • Terodiline  • Tetrahydropalmatine  • Tetrandrine  • Tolfenamic acid  • Tranilast


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  2. ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
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