Cinchocaine
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It has been suggested that this article or section be merged with Dibucaine number. (Discuss) Proposed since November 2009. |
| File:Cinchocaine.svg | |
| Systematic (IUPAC) name | |
|---|---|
|
2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide | |
| Clinical data | |
| Routes of administration | topical, intravenous (equine euthanasia) |
| Identifiers | |
| CAS Number | 85-79-0 |
| ATC code | C05AD04 (WHO) D04AB02 N01BB06 S01HA06 |
| PubChem | CID 3025 |
| DrugBank | APRD00915 |
| ChemSpider | 2917 |
| Chemical data | |
| Formula | C20H29N3O2 |
| Molar mass | 343.463 g/mol[[Script error: No such module "String".]] |
| Script error: No such module "collapsible list". | |
| (verify) | |
Cinchocaine (or Dibucaine) is an amide local anesthetic. It is the active ingredient in some topical hemorrhoid creams such as Proctosedyl. It is sold under the brand names Cincain, Nupercainal, Nupercaine and Sovcaine [1].
Dibucaine is insoluble in alkaline aquatic environments.
It is also a component of the veterinary drug Somulose, used for euthanasia of horses and cattle.
External links
- Abdel-Ghani N, Youssef A, Awady M (2005). "Cinchocaine hydrochloride determination by atomic absorption spectrometry and spectrophotometry". Farmaco. 60 (5): 419–24. doi:10.1016/j.farmac.2005.03.001. PMID 15910814.
- Souto-Padron T, Lima AP, de Oliveira Ribeiro R. (2006). "Effects of dibucaine on the endocytic/exocytic pathways in Trypanosoma cruzi". Parasitol Res. 99 (4): 317. doi:10.1007/s00436-006-0192-1. PMID 16612626.
- Nounou M, El-Khordagui L, Khalafallah N (2005). "Effect of various formulation variables on the encapsulation and stability of dibucaine base in multilamellar vesicles". Acta Pol Pharm. 62 (5): 369–79. PMID 16459486.
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