Gallamine triethiodide
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File:Gallamine.svg | |
Systematic (IUPAC) name | |
---|---|
2,2',2''-[benzene-1,2,3-triyltris(oxy)]tris(N,N-diethylethanamine) | |
Identifiers | |
CAS Number |
65-29-2 (triethiodide) |
ATC code | M03AC02 (WHO) |
PubChem | CID 67425 |
IUPHAR/BPS | 356 |
DrugBank | APRD00712 |
Chemical data | |
Formula |
C24H45N3O3 C30H60N3O3+3 · 3 I- (gallamine triethiodide) |
Molar mass |
423.633 g/mol 891.529 g/mol (triethiodide) |
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Gallamine (Flaxedil) is a non-depolarising muscle relaxant.[1] It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine.[2] Gallamine has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension. Very high doses cause histamine release.
Gallamine is commonly used to stabilize muscle contractions during surgical procedures.
It was developed by Daniel Bovet in 1947.[3]
References
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45px | This drug article relating to the musculoskeletal system is a stub. You can help ssf by expanding it. |
- ↑ "Webster's Online Dictionary - Flaxedil". Retrieved 2008-12-15.
- ↑ "RxMed: Pharmaceutical Information - FLAXEDIL". Retrieved 2008-12-15.
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
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