Indometacin farnesil
From Self-sufficiency
File:Infree.png | |
Systematic (IUPAC) name | |
---|---|
(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetate | |
Clinical data | |
Routes of administration | Oral |
Legal status | |
Legal status |
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Pharmacokinetic data | |
Metabolism | To indometacin |
Biological half-life | 1.5 hours |
Excretion | Renal |
Identifiers | |
CAS Number | 85801-02-1 |
PubChem | CID 5282183 |
Chemical data | |
Formula | C34H40ClNO4 |
Molar mass | 562.14 g/mol[[Script error: No such module "String".]] |
Script error: No such module "collapsible list". |
Indometacin farnesil (INN) is a prodrug of the non-steroidal anti-inflammatory drug indometacin, designed to reduce the occurrence of side-effects by esterification of the carboxyl group on indometacin with farnesol. Indometacin farnesil was first approved in Japan in 1991, and is available in Japan and Indonesia, under the trade names Infree and Dialon respectively.
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