Proglumetacin
From Self-sufficiency
File:Proglumetacin.svg | |
Systematic (IUPAC) name | |
---|---|
3-{4-[2-({[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl}oxy)ethyl]piperazin-1-yl}propyl N2-benzoyl-N,N-dipropyl-α-glutaminate | |
Pharmacokinetic data | |
Metabolism | Hepatic. Undergoes enterohepatic recirculation |
Identifiers | |
CAS Number | 57132-53-3 59209-40-4 (maleate) |
ATC code | M01AB14 (WHO) |
PubChem | CID 4921 |
Synonyms | 3-[4-[2-[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl]oxyethyl]piperazin-1-yl]propyl 4-(benzoylamino)-5-(dipropylamino)-5-oxopentanoate |
Chemical data | |
Formula | C46H58ClN5O8 |
Molar mass | 844.43442 g/mol[[Script error: No such module "String".]] |
Proglumetacin (usually as the maleate salt, trade names Afloxan, Protaxon and Proxil) is a non-steroidal anti-inflammatory drug. It is metabolized in the body to indometacin and proglumide,[1] a drug with antisecretory effects that helps prevent injury to the stomach lining.
References
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