Nabumetone

From Self-sufficiency
Revision as of 05:36, 23 August 2010 by Nirmos (Talk) (Removed two redundant categories.)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Nabumetone
File:Nabumetone.svg
Systematic (IUPAC) name
4-(6-methoxy-2-naphthyl)-2-butanone
Clinical data
Routes of
administration		 Oral
Legal status
Legal status
  • POM
Pharmacokinetic data
Protein binding > 99% (active metabolite)
Metabolism Hepatic, to active metabolite 6-methoxy-2-naphthylacetic acid; 6-MNA
Biological half-life 23 hours (active metabolite)
Excretion Renal
Identifiers
CAS Number 42924-53-8
ATC code M01AX01 (WHO)
PubChem CID 4409
DrugBank APRD01128
Chemical data
Formula C15H16O2
Molar mass 228.29 g/mol[[Script error: No such module "String".]]
  (verify)
Script error: No such module "TemplatePar".Expression error: Unexpected < operator.

Nabumetone is a non-steroidal anti-inflammatory drug[1] (NSAID), the only 1-naphthaleneacetic acid derivative. Nabumetone has been developed by Beecham. It is available under numerous brand names, such as Relafen, Relifex and Gambaran.

It is used to treat pain or inflammation caused by arthritis. Nabumetone works by reducing the effects of hormones that cause pain and inflammation.

It has been shown to have a slightly lower risk of gastrointestinal side effects than most other non-selective NSAIDs.

References

Cite error: Invalid <references> tag; parameter "group" is allowed only.

Use <references />, or <references group="..." />
Pyrazolidine/Butylpyrazolidines
Acetic acid derivatives
and related substances
Oxicams
Propionic acid derivatives
Fenamates
Coxibs
Other

M: MUS, DF+DRCT

anat (h/n, u, t/d, a/p, l)/phys/hist

noco(m, s, c)/cong(d)/tumr, sysi/epon, injr

proc, drug (M1A/3)

Non-steroidal anti-inflammatory drug (NSAID) products (primarily M01A and M02A, also N02BA)
Salicylates
Arylalkanoic acids
2-Arylpropionic acids
(profens)
N-Arylanthranilic acids
(fenamic acids)
Pyrazolidine derivatives
Oxicams
COX-2 inhibitors
Sulfonanilides
Topically used products
COX-inhibiting nitric oxide donators
Others
Items listed in bold indicate initially developed compounds of specific groups. †Withdrawn drugs. ‡Veterinary use medications.
45px This drug article relating to the musculoskeletal system is a stub. You can help ssf by expanding it.
40px This analgesic-related article is a stub. You can help ssf by expanding it.
de:Nabumeton

it:Nabumetone nl:Nabumeton pl:Nabumeton pt:Nabumetona sv:Nabumeton

vi:Nabumetone
  1. ↑ Gonzalo-Garijo MA, Cordobés-Duran C, Lamilla-Yerga AM, Moreno-Gastón I (2007). "Severe immediate reaction to nabumetone". Journal of investigational allergology & clinical immunology : official organ of the International Association of Asthmology (INTERASMA) and Sociedad Latinoamericana de Alergia e Inmunología. 17 (4): 274–6. PMID 17694703. 
Retrieved from "http://ssf.f15ijp.com/wiki/index.php?title=Nabumetone&oldid=28420"