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File:NGD-4715 structure.png
Systematic (IUPAC) name
Chemical data
Formula C19H24BrN3O3
Molar mass 422.315[[Script error: No such module "String".]]
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NGD-4715 is a drug being developed by Neurogen, which acts as a selective, non-peptide antagonist at the melanin concentrating hormone receptor MCH1. In animal studies it has anxiolytic, antidepressant and anorectic effects,[1] and it has successfully passed Phase I clinical trials in humans.[2]


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  1. Chaki S, Kanuma K. Neuropeptide receptors: Novel therapeutic targets for depression and anxiety disorders. Drugs of the Future. 2007;32(9):809.
  2. Neurogen Announces Results of First-in-Human Trial for New Approach to Treating Obesity. Business Wire. May 2 2007