NGD-4715
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File:NGD-4715 structure.png | |
Systematic (IUPAC) name | |
---|---|
1-(3,4-dimethoxybenzyl)-4-(5-bromo-6-methoxypyridin-2-yl)piperazine | |
Chemical data | |
Formula | C19H24BrN3O3 |
Molar mass | 422.315[[Script error: No such module "String".]] |
Script error: No such module "collapsible list". |
NGD-4715 is a drug being developed by Neurogen, which acts as a selective, non-peptide antagonist at the melanin concentrating hormone receptor MCH1. In animal studies it has anxiolytic, antidepressant and anorectic effects,[1] and it has successfully passed Phase I clinical trials in humans.[2]
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References
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- Jump up ↑ Chaki S, Kanuma K. Neuropeptide receptors: Novel therapeutic targets for depression and anxiety disorders. Drugs of the Future. 2007;32(9):809.
- Jump up ↑ Neurogen Announces Results of First-in-Human Trial for New Approach to Treating Obesity. Business Wire. May 2 2007
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