GW-803,430
File:GW-803,430 structure.png |
Systematic (IUPAC) name |
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6-(4-chlorophenyl)-3-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-3H-thieno[3,2-d]pyrimidin-4-one |
Identifiers |
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ATC code |
none |
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Chemical data |
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Formula |
C25H24ClN3O3S |
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Molar mass |
481.993 g/mol[[Script error: No such module "String".]] |
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GW-803,430 (GW-3430) is a drug used in scientific research and is a selective non-peptide antagonist at the melanin concentrating hormone receptor MCH1. In animal studies it has anxiolytic, antidepressant and anorectic effects.[1][2]
References
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Serotonin modulators and stimulators (SMSs) | |
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Cholecystokinin | |
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CRH | |
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Galanin | |
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Ghrelin | |
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MCH | |
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Melanocortin | |
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Neuropeptide S | |
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Neuropeptide Y | |
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Neurotensin | |
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Opioid | |
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Orexin | |
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Oxytocin | |
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Tachykinin | | Agonists: Substance PAntagonists: Aprepitant • Befetupitant • Casopitant • CI-1021 • CP-96,345 • CP-99,994 • CP-122,721 • Dapitant • Ezlopitant • FK-888 • Fosaprepitant • GR-203,040 • GW-597,599 • HSP-117 • L-733,060 • L-741,671 • L-743,310 • L-758,298 • Lanepitant • LY-306,740 • Maropitant • Netupitant • NKP-608 • Nolpitantium • Orvepitant • RP-67,580 • SDZ NKT 343 • Vestipitant • Vofopitant |
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Vasopressin | |
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- Jump up ↑ Chaki S, Kanuma K. Neuropeptide receptors: Novel therapeutic targets for depression and anxiety disorders. Drugs of the Future. 2007;32(9):809.
- Jump up ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.