OR1E1

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Olfactory receptor, family 1, subfamily E, member 1
Identifiers
Symbols	OR1E1; OR17-2; HGM071; OR13-66; OR17-32; OR1E5; OR1E6; OR1E8P; OR1E9P; OST547
External IDs	MGI: 109315 HomoloGene: 73918 GeneCards: OR1E1 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
RNA expression pattern
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More reference expression data
Orthologs
Species	Human	Mouse
Entrez	8387	258925
Ensembl	ENSG00000180016	ENSMUSG00000062128
UniProt	P30953	n/a
RefSeq (mRNA)	NM_003553	NM_146923
RefSeq (protein)	NP_003544	NP_667134
Location (UCSC)	Chr 17: 3.25 - 3.25 Mb	Chr 11: 73.17 - 73.17 Mb
PubMed search	[1]	[2]

Olfactory receptor 1E1 is a protein that in humans is encoded by the OR1E1 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Rouquier S, Taviaux S, Trask BJ; et al. (1998). "Distribution of olfactory receptor genes in the human genome". Nat. Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Glusman G, Sosinsky A, Ben-Asher E; et al. (2000). "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster". Genomics. 63 (2): 227–45. doi:10.1006/geno.1999.6030. PMID 10673334. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. doi:10.1073/pnas.040580197. PMC 16022 Freely accessible. PMID 10706615. CS1 maint: Multiple names: authors list (link)
• Fuchs T, Malecova B, Linhart C; et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR1E1+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.