OR2AG1

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Olfactory receptor, family 2, subfamily AG, member 1
Identifiers
Symbols	OR2AG1; OR11-79; OR2AG3
External IDs	MGI: 3030539 HomoloGene: 12558 GeneCards: OR2AG1 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	144125	259034
Ensembl	ENSG00000170803	ENSMUSG00000047120
UniProt	Q9H205	n/a
RefSeq (mRNA)	NM_001004489	NM_147032
RefSeq (protein)	NP_001004489	NP_667243
Location (UCSC)	Chr 11: 6.76 - 6.76 Mb	Chr 7: 106.67 - 106.67 Mb
PubMed search	[1]	[2]

Olfactory receptor 2AG1 is a protein that in humans is encoded by the OR2AG1 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Lane RP, Cutforth T, Young J; et al. (2001). "Genomic analysis of orthologous mouse and human olfactory receptor loci". Proc. Natl. Acad. Sci. U.S.A. 98 (13): 7390–5. doi:10.1073/pnas.131215398. PMC 34679 Freely accessible. PMID 11416212. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fuchs T, Malecova B, Linhart C; et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)
• Neuhaus EM, Mashukova A, Zhang W; et al. (2006). "A specific heat shock protein enhances the expression of mammalian olfactory receptor proteins". Chem. Senses. 31 (5): 445–52. doi:10.1093/chemse/bjj049. PMID 16565291. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mashukova A, Spehr M, Hatt H, Neuhaus EM (2006). "Beta-arrestin2-mediated internalization of mammalian odorant receptors". J. Neurosci. 26 (39): 9902–12. doi:10.1523/JNEUROSCI.2897-06.2006. PMID 17005854. CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR2AG1+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.