OR5AS1

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Olfactory receptor, family 5, subfamily AS, member 1
Identifiers
Symbols	OR5AS1; OR11-168
External IDs	MGI: 3030945 HomoloGene: 74238 GeneCards: OR5AS1 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	219447	258586
Ensembl	ENSG00000181785	ENSMUSG00000075158
UniProt	Q8N127	n/a
RefSeq (mRNA)	NM_001001921	NM_146593
RefSeq (protein)	NP_001001921	NP_666804
Location (UCSC)	Chr 11: 55.55 - 55.56 Mb	Chr 2: 86.95 - 86.95 Mb
PubMed search	[1]	[2]

Olfactory receptor 5AS1 is a protein that in humans is encoded by the OR5AS1 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR5AS1+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.