OR2A12
| edit |
| Olfactory receptor, family 2, subfamily A, member 12 | |||||||||||
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| Identifiers | |||||||||||
| Symbols | OR2A12; OR2A12P; OR2A16P | ||||||||||
| External IDs | MGI: 3030280 HomoloGene: 17179 GeneCards: OR2A12 Gene | ||||||||||
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| Orthologs | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | 346525 | 258292 | |||||||||
| Ensembl | n/a | ENSMUSG00000073111 | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | NM_001004135 | NM_146295 | |||||||||
| RefSeq (protein) | NP_001004135 | NP_666407 | |||||||||
| Location (UCSC) | n/a | Chr 6: 42.86 - 42.86 Mb | |||||||||
| PubMed search | [1] | [2] | |||||||||
Olfactory receptor 2A12 is a protein that in humans is encoded by the OR2A12 gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
See also
References
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<references />, or <references group="..." />Further reading
- Fuchs T, Malecova B, Linhart C; et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
- Gilad Y, Lancet D (2003). "Population differences in the human functional olfactory repertoire". Mol. Biol. Evol. 20 (3): 307–14. doi:10.1093/molbev/msg013. PMID 12644552.
- Scherer SW, Cheung J, MacDonald JR; et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961 Freely accessible. PMID 12690205.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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