OR8K5

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Olfactory receptor, family 8, subfamily K, member 5
Identifiers
Symbols	OR8K5; OR11-174
External IDs	MGI: 3030842 HomoloGene: 74197 GeneCards: OR8K5 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	219453	258866
Ensembl	ENSG00000181752	ENSMUSG00000050603
UniProt	Q8NH50	n/a
RefSeq (mRNA)	NM_001004058	XM_001001571
RefSeq (protein)	NP_001004058	XP_001001571
Location (UCSC)	Chr 11: 55.68 - 55.68 Mb	Chr 2: 85.49 - 85.49 Mb
PubMed search	[1]	[2]

Olfactory receptor 8K5 is a protein that in humans is encoded by the OR8K5 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR8K5+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.