OR51B2

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Olfactory receptor, family 51, subfamily B, member 2
Identifiers
Symbols	OR51B2; HOR5'Beta3; OR51B1P
External IDs	MGI: 1341900 HomoloGene: 56593 GeneCards: OR51B2 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
Orthologs
Species	Human	Mouse
Entrez	79345	18366
Ensembl	ENSG00000184881	ENSMUSG00000063615
UniProt	Q9Y5P1	n/a
RefSeq (mRNA)	NM_033180	NM_013617
RefSeq (protein)	NP_149420	NP_038645
Location (UCSC)	Chr 11: 5.3 - 5.3 Mb	Chr 7: 103.77 - 103.77 Mb
PubMed search	[1]	[2]

Olfactory receptor 51B2 is a protein that in humans is encoded by the OR51B2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Bulger M, van Doorninck JH, Saitoh N; et al. (1999). "Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes". Proc. Natl. Acad. Sci. U.S.A. 96 (9): 5129–34. doi:10.1073/pnas.96.9.5129. PMC 21828 Freely accessible. PMID 10220430. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bulger M, Bender MA, van Doorninck JH; et al. (2001). "Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14560–5. doi:10.1073/pnas.97.26.14560. PMC 18958 Freely accessible. PMID 11121057. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fuchs T, Malecova B, Linhart C; et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR51B2+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.