OR8H3

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Olfactory receptor, family 8, subfamily H, member 3
Identifiers
Symbols	OR8H3; OR11-172
External IDs	MGI: 3030934 HomoloGene: 34954 GeneCards: OR8H3 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	390152	258587
Ensembl	ENSG00000181761	ENSMUSG00000070875
UniProt	Q8N146	n/a
RefSeq (mRNA)	NM_001005201	NM_146594
RefSeq (protein)	NP_001005201	NP_666805
Location (UCSC)	Chr 11: 55.65 - 55.65 Mb	Chr 2: 86.78 - 86.78 Mb
PubMed search	[1]	[2]

Olfactory receptor 8H3 is a protein that in humans is encoded by the OR8H3 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR8H3+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.