OR6C4
| edit |
| Olfactory receptor, family 6, subfamily C, member 4 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | OR6C4; OR12-10 | ||||||||||||
| External IDs | MGI: 3030599 HomoloGene: 79371 GeneCards: OR6C4 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
| 250px | |||||||||||||
| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 341418 | 258315 | |||||||||||
| Ensembl | ENSG00000179626 | ENSMUSG00000056853 | |||||||||||
| UniProt | Q8NGE1 | n/a | |||||||||||
| RefSeq (mRNA) | NM_001005494 | NM_146318 | |||||||||||
| RefSeq (protein) | NP_001005494 | NP_666430 | |||||||||||
| Location (UCSC) | Chr 12: 54.23 - 54.23 Mb | Chr 10: 128.45 - 128.45 Mb | |||||||||||
| PubMed search | [1] | [2] | |||||||||||
Olfactory receptor 6C4 is a protein that in humans is encoded by the OR6C4 gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
See also
References
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- Lauzurica P, Bragado R, López D; et al. (1992). "Asymmetric selection of T cell antigen receptor alpha- and beta-chains in HLA-B27 alloreactivity". J. Immunol. 148 (11): 3624–30. PMID 1316921.
- Youngblood K, Fruchter L, Ding G; et al. (1994). "Rheumatoid factors from the peripheral blood of two patients with rheumatoid arthritis are genetically heterogeneous and somatically mutated". J. Clin. Invest. 93 (2): 852–61. doi:10.1172/JCI117040. PMC 293948 Freely accessible. PMID 7509350.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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