OR2L8

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Olfactory receptor, family 2, subfamily L, member 8
Identifiers
Symbols	OR2L8;
External IDs	MGI: 3030002 HomoloGene: 84569 GeneCards: OR2L8 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
Orthologs
Species	Human	Mouse
Entrez	391190	258354
Ensembl	ENSG00000196936	ENSMUSG00000061361
UniProt	Q8NGY9	n/a
RefSeq (mRNA)	NM_001001963	NM_146357
RefSeq (protein)	NP_001001963	NP_666469
Location (UCSC)	Chr 1: 246.18 - 246.18 Mb	Chr 16: 19.44 - 19.44 Mb
PubMed search	[1]	[2]

Olfactory receptor 2L8 is a protein that in humans is encoded by the OR2L8 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)

{== External links ==

• MeSH OR2L8+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.