OR8D4

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Olfactory receptor, family 8, subfamily D, member 4
Identifiers
Symbols	OR8D4; OR11-275
External IDs	MGI: 3030819 HomoloGene: 17416 GeneCards: OR8D4 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
RNA expression pattern
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More reference expression data
Orthologs
Species	Human	Mouse
Entrez	338662	258854
Ensembl	ENSG00000181518	ENSMUSG00000049073
UniProt	Q8NGM9	n/a
RefSeq (mRNA)	NM_001005197	NM_146855
RefSeq (protein)	NP_001005197	NP_667066
Location (UCSC)	Chr 11: 123.28 - 123.28 Mb	Chr 9: 39.88 - 39.88 Mb
PubMed search	[1]	[2]

Olfactory receptor 8D4 is a protein that in humans is encoded by the OR8D4 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR8D4+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.