OR51E1

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Olfactory receptor, family 51, subfamily E, member 1
Identifiers
Symbols	OR51E1; D-GPCR; GPR164; MGC24137; OR51E1P; OR52A3P; POGR; PSGR2
External IDs	MGI: 3030392 HomoloGene: 17503 GeneCards: OR51E1 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	143503	259097
Ensembl	ENSG00000180785	ENSMUSG00000070423
UniProt	Q8TCB6	n/a
RefSeq (mRNA)	NM_152430	NM_147093
RefSeq (protein)	NP_689643	NP_667304
Location (UCSC)	Chr 11: 4.62 - 4.63 Mb	Chr 7: 102.58 - 102.59 Mb
PubMed search	[1]	[2]

Olfactory receptor 51E1 is a protein that in humans is encoded by the OR51E1 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Wang J, Weng J, Cai Y; et al. (2006). "The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase". Prostate. 66 (8): 847–57. doi:10.1002/pros.20389. PMID 16491480. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Weng J, Wang J, Hu X; et al. (2007). "PSGR2, a novel G-protein coupled receptor, is overexpressed in human prostate cancer". Int. J. Cancer. 118 (6): 1471–80. doi:10.1002/ijc.21527. PMID 16206286. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Weigle B, Fuessel S, Ebner R; et al. (2004). "D-GPCR: a novel putative G protein-coupled receptor overexpressed in prostate cancer and prostate". Biochem. Biophys. Res. Commun. 322 (1): 239–49. doi:10.1016/j.bbrc.2004.07.106. PMID 15313197. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)
• Vanti WB, Nguyen T, Cheng R; et al. (2003). "Novel human G-protein-coupled receptors". Biochem. Biophys. Res. Commun. 305 (1): 67–71. doi:10.1016/S0006-291X(03)00709-5. PMID 12732197. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Adams MD, Kerlavage AR, Fleischmann RD; et al. (1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence". Nature. 377 (6547 Suppl): 3–174. doi:10.1038/377003a0. PMID 7566098. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR51E1+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.