OR7A5

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Olfactory receptor, family 7, subfamily A, member 5
Identifiers
Symbols	OR7A5; HTPCR2
External IDs	HomoloGene: 81853 GeneCards: OR7A5 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • spermatogenesis • sensory perception of smell • response to stimulus Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	26659	n/a
Ensembl	ENSG00000188269	n/a
UniProt	Q15622	n/a
RefSeq (mRNA)	NM_017506	n/a
RefSeq (protein)	NP_059976	n/a
Location (UCSC)	Chr 19: 14.8 - 14.8 Mb	n/a
PubMed search	[1]	n/a

Olfactory receptor 7A5 is a protein that in humans is encoded by the OR7A5 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Grimwood J, Gordon LA, Olsen A; et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fuchs T, Malecova B, Linhart C; et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (1997). "Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome". Biochem. Biophys. Res. Commun. 237 (2): 283–7. doi:10.1006/bbrc.1997.7043. PMID 9268701. CS1 maint: Multiple names: authors list (link)
• Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species". Genomics. 39 (3): 239–46. doi:10.1006/geno.1996.4490. PMID 9119360. CS1 maint: Multiple names: authors list (link)
• Parmentier M, Libert F, Schurmans S; et al. (1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–5. doi:10.1038/355453a0. PMID 1370859. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR7A5+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.