OR51I2

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Olfactory receptor, family 51, subfamily I, member 2
Identifiers
Symbols	OR51I2; OR11-38
External IDs	MGI: 3030475 HomoloGene: 17489 GeneCards: OR51I2 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
RNA expression pattern
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More reference expression data
Orthologs
Species	Human	Mouse
Entrez	390064	259075
Ensembl	ENSG00000187918	ENSMUSG00000073932
UniProt	Q9H344	n/a
RefSeq (mRNA)	NM_001004754	NM_147072
RefSeq (protein)	NP_001004754	NP_667283
Location (UCSC)	Chr 11: 5.43 - 5.43 Mb	Chr 7: 103.91 - 103.91 Mb
PubMed search	[1]	[2]

Olfactory receptor 51I2 is a protein that in humans is encoded by the OR51I2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Bulger M, van Doorninck JH, Saitoh N; et al. (1999). "Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes". Proc. Natl. Acad. Sci. U.S.A. 96 (9): 5129–34. doi:10.1073/pnas.96.9.5129. PMC 21828 Freely accessible. PMID 10220430. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bulger M, Bender MA, van Doorninck JH; et al. (2001). "Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14560–5. doi:10.1073/pnas.97.26.14560. PMC 18958 Freely accessible. PMID 11121057. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR51I2+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.