OR3A1

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Olfactory receptor, family 3, subfamily A, member 1
Identifiers
Symbols	OR3A1; OLFRA03; OR17-40; OR17-82; OR40
External IDs	MGI: 3030236 HomoloGene: 1915 GeneCards: OR3A1 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • integral to plasma membrane • membrane • integral to membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4994	258703
Ensembl	ENSG00000180090	ENSMUSG00000070379
UniProt	P47881	n/a
RefSeq (mRNA)	NM_002550	NM_146708
RefSeq (protein)	NP_002541	NP_666919
Location (UCSC)	Chr 17: 3.14 - 3.14 Mb	Chr 11: 73.97 - 73.97 Mb
PubMed search	[1]	[2]

Olfactory receptor 3A1 is a protein that in humans is encoded by the OR3A1 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Marrakchi M, Vidic J, Jaffrezic-Renault N; et al. (2008). "A new concept of olfactory biosensor based on interdigitated microelectrodes and immobilized yeasts expressing the human receptor OR17-40". Eur. Biophys. J. 36 (8): 1015–8. doi:10.1007/s00249-007-0187-6. PMID 17579849. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jacquier V, Prummer M, Segura JM; et al. (2006). "Visualizing odorant receptor trafficking in living cells down to the single-molecule level". Proc. Natl. Acad. Sci. U.S.A. 103 (39): 14325–30. doi:10.1073/pnas.0603942103. PMC 1599963 Freely accessible. PMID 16980412. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Glusman G, Sosinsky A, Ben-Asher E; et al. (2000). "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster". Genomics. 63 (2): 227–45. doi:10.1006/geno.1999.6030. PMID 10673334. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ben-Arie N, Lancet D, Taylor C; et al. (1994). "Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire". Hum. Mol. Genet. 3 (2): 229–35. doi:10.1093/hmg/3.2.229. PMID 8004088. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR3A1+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.