OR2H2

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Olfactory receptor, family 2, subfamily H, member 2
Identifiers
Symbols	OR2H2; FAT11; MGC126732; MGC138381; OLFR 42B; OLFR2; OR2H3; dJ271M21.2; hs6M1-12
External IDs	OMIM: 600578 MGI: 2177473 HomoloGene: 68546 GeneCards: OR2H2 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • membrane • integral to membrane Biological process • defense response • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • mating • response to stimulus Sources: Amigo / EGO
RNA expression pattern
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More reference expression data
Orthologs
Species	Human	Mouse
Entrez	7932	258469
Ensembl	ENSG00000204657	ENSMUSG00000056600
UniProt	O95918	n/a
RefSeq (mRNA)	NM_007160	NM_146477
RefSeq (protein)	NP_009091	NP_666688
Location (UCSC)	Chr 6: 29.66 - 29.66 Mb	Chr 17: 36.69 - 36.69 Mb
PubMed search	[1]	[2]

Olfactory receptor 2H2 is a protein that in humans is encoded by the OR2H2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fan W, Liu YC, Parimoo S, Weissman SM (1995). "Olfactory receptor-like genes are located in the human major histocompatibility complex". Genomics. 27 (1): 119–23. doi:10.1006/geno.1995.1013. PMID 7665158. CS1 maint: Multiple names: authors list (link)
• Fan W, Cai W, Parimoo S; et al. (1996). "Identification of seven new human MHC class I region genes around the HLA-F locus". Immunogenetics. 44 (2): 97–103. doi:10.1007/BF02660056. PMID 8662070. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Eklund AC, Belchak MM, Lapidos K; et al. (2000). "Polymorphisms in the HLA-linked olfactory receptor genes in the Hutterites". Hum. Immunol. 61 (7): 711–7. doi:10.1016/S0198-8859(00)00132-4. PMID 10880742. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Younger RM, Amadou C, Bethel G; et al. (2001). "Characterization of clustered MHC-linked olfactory receptor genes in human and mouse". Genome Res. 11 (4): 519–30. doi:10.1101/gr.160301. PMC 311051 Freely accessible. PMID 11282967. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fuchs T, Malecova B, Linhart C; et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Volz A, Ehlers A, Younger R; et al. (2003). "Complex transcription and splicing of odorant receptor genes". J. Biol. Chem. 278 (22): 19691–701. doi:10.1074/jbc.M212424200. PMID 12637542. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mungall AJ, Palmer SA, Sims SK; et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR2H2+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.