OR3A3
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Olfactory receptor, family 3, subfamily A, member 3 | |||||||||||||
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Identifiers | |||||||||||||
Symbols | OR3A3; OR17-137; OR17-16; OR17-201; OR3A6; OR3A7; OR3A8P | ||||||||||||
External IDs | MGI: 3030245 HomoloGene: 74999 GeneCards: OR3A3 Gene | ||||||||||||
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RNA expression pattern | |||||||||||||
250px | |||||||||||||
More reference expression data | |||||||||||||
Orthologs | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | 8392 | 258704 | |||||||||||
Ensembl | ENSG00000159961 | ENSMUSG00000054406 | |||||||||||
UniProt | P47888 | n/a | |||||||||||
RefSeq (mRNA) | NM_012373 | NM_146709 | |||||||||||
RefSeq (protein) | NP_036505 | NP_666920 | |||||||||||
Location (UCSC) | Chr 17: 3.27 - 3.27 Mb | Chr 11: 74.16 - 74.16 Mb | |||||||||||
PubMed search | [1] | [2] |
Olfactory receptor 3A3 is a protein that in humans is encoded by the OR3A3 gene.[1][2][3]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]
See also
References
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Further reading
- Zody MC, Garber M, Adams DJ; et al. (2006). "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage". Nature. 440 (7087): 1045–9. doi:10.1038/nature04689. PMC 2610434 Freely accessible. PMID 16625196.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052.
- Gilad Y, Lancet D (2003). "Population differences in the human functional olfactory repertoire". Mol. Biol. Evol. 20 (3): 307–14. doi:10.1093/molbev/msg013. PMID 12644552.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932.
- Fuchs T, Malecova B, Linhart C; et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
- Glusman G, Sosinsky A, Ben-Asher E; et al. (2000). "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster". Genomics. 63 (2): 227–45. doi:10.1006/geno.1999.6030. PMID 10673334.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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- ↑ 3.0 3.1 "Entrez Gene: OR3A3 olfactory receptor, family 3, subfamily A, member 3".
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