OR6A2

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Olfactory receptor, family 6, subfamily A, member 2
Identifiers
Symbols	OR6A2; I7; MGC126538; MGC126540; OR11-55; OR6A1; OR6A2P
External IDs	OMIM: 608495 MGI: 97432 HomoloGene: 2743 GeneCards: OR6A2 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • integral to plasma membrane • membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	8590	18317
Ensembl	ENSG00000184933	ENSMUSG00000070417
UniProt	O95222	n/a
RefSeq (mRNA)	NM_003696	NM_010983
RefSeq (protein)	NP_003687	NP_035113
Location (UCSC)	Chr 11: 6.77 - 6.77 Mb	Chr 7: 106.79 - 106.8 Mb
PubMed search	[1]	[2]

Olfactory receptor 6A2 is a protein that in humans is encoded by the OR6A2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Buettner JA, Glusman G, Ben-Arie N; et al. (1998). "Organization and evolution of olfactory receptor genes on human chromosome 11". Genomics. 53 (1): 56–68. doi:10.1006/geno.1998.5422. PMID 9787077. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lane RP, Cutforth T, Young J; et al. (2001). "Genomic analysis of orthologous mouse and human olfactory receptor loci". Proc. Natl. Acad. Sci. U.S.A. 98 (13): 7390–5. doi:10.1073/pnas.131215398. PMC 34679 Freely accessible. PMID 11416212. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 Freely accessible. PMID 12477932. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 Freely accessible. PMID 15489334. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR6A2+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.