OR1J2

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Olfactory receptor, family 1, subfamily J, member 2
Identifiers
Symbols	OR1J2; FLJ16828; HG152; HSA5; OR1J3; OR1J5; OR9-19; OST044
External IDs	MGI: 3030186 HomoloGene: 73996 GeneCards: OR1J2 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • integral to membrane Biological process • G-protein coupled receptor protein signaling pathway • sensory perception of smell
Orthologs
Species	Human	Mouse
Entrez	26740	258942
Ensembl	n/a	ENSMUSG00000053146
UniProt	n/a	n/a
RefSeq (mRNA)	NM_054107	NM_146940
RefSeq (protein)	NP_473448	NP_667151
Location (UCSC)	n/a	Chr 2: 36.69 - 36.69 Mb
PubMed search	[1]	[2]

Olfactory receptor 1J2 is a protein that in humans is encoded by the OR1J2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Parmentier M, Libert F, Schurmans S; et al. (1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–5. doi:10.1038/355453a0. PMID 1370859. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. doi:10.1073/pnas.040580197. PMC 16022 Freely accessible. PMID 10706615. CS1 maint: Multiple names: authors list (link)
• Fuchs T, Malecova B, Linhart C; et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gilad Y, Bustamante CD, Lancet D, Pääbo S (2003). "Natural selection on the olfactory receptor gene family in humans and chimpanzees". Am. J. Hum. Genet. 73 (3): 489–501. doi:10.1086/378132. PMC 1180675 Freely accessible. PMID 12908129. CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993 Freely accessible. PMID 14983052. CS1 maint: Multiple names: authors list (link)

External links

• MeSH OR1J2+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.